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1cdw
From Proteopedia
| 1cdw, resolution 1.90Å () | |||||
|---|---|---|---|---|---|
| Domains: | TBP_eukaryotes, SPT15 | ||||
| |||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||
| Coordinates: | save as pdb, mmCIF, xml | ||||
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of the C-terminal/core region of human TBP complexed with the TATA element of the adenovirus major late promoter has been determined at 1.9 angstroms resolution. Structural and functional analyses of the protein-DNA complex are presented, with a detailed comparison to our 1.9-angstroms resolution structure of Arabidopsis thaliana TBP2 bound to the same TATA box.
Crystal structure of a human TATA box-binding protein/TATA element complex., Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:8643494
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1CDW is a Single protein structure of sequence from Homo sapiens. Additional information on 1CDW is available in a page on TATA-Binding Protein at the RCSB PDB Molecule of the Month. Full crystallographic information is available from OCA.
Reference
Crystal structure of a human TATA box-binding protein/TATA element complex., Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:8643494
Page seeded by OCA on Wed Jul 23 10:56:18 2008
