Structural highlights
Function
YACG_ECOLI Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Sengupta S, Nagaraja V. YacG from Escherichia coli is a specific endogenous inhibitor of DNA gyrase. Nucleic Acids Res. 2008 Aug;36(13):4310-6. doi: 10.1093/nar/gkn355. Epub 2008 Jun, 27. PMID:18586829 doi:http://dx.doi.org/10.1093/nar/gkn355