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1ytf

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1ytf, resolution 2.50Å ()
Domains: TOA2, TFIIA_gamma_N, TFIIA_gamma_C, TOA1, SPT15, TBP_eukaryotes
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



YEAST TFIIA/TBP/DNA COMPLEX

Publication Abstract from PubMed

The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.

Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

About this Structure

1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. Additional information on 1YTF is available in a page on TATA-Binding Protein at the RCSB PDB Molecule of the Month. Full crystallographic information is available from OCA.

Reference

Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010

Page seeded by OCA on Wed Jul 23 11:07:24 2008

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