2d1p

From Proteopedia

crystal structure of heterohexameric TusBCD proteins, which are crucial for the tRNA modification

Structural highlights

2d1p is a 9 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.15Å
Ligands:	SO4
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TUSD_ECOLI Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.^[1]

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Ikeuchi Y, Shigi N, Kato J, Nishimura A, Suzuki T. Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions. Mol Cell. 2006 Jan 6;21(1):97-108. PMID:16387657 doi:http://dx.doi.org/S1097-2765(05)01761-2

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 References

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PDB ID 2d1p

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2d1p

From Proteopedia

crystal structure of heterohexameric TusBCD proteins, which are crucial for the tRNA modification

Structural highlights

Function

Evolutionary Conservation

References

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