2dgy

Structural highlights

Function

[EIF1A_HUMAN] Plays a role into cellular response to oxidative stress. Decreases cell proliferation.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Rakitina TV, Bogatova OV, Smirnova EV, Pozdeev VI, Kostanian IA, Lipkin VM. [Haponin (eIF1AD) interacts with glyceraldehyde 3-phosphate dehydrogenase in the CHO-K1 cell line]. Bioorg Khim. 2010 May-Jun;36(3):312-8. PMID:20644585
2. ↑ Smirnova EV, Rakitina TV, Bogatova OV, Ivanova DL, Vorobyeva EE, Lipkin AV, Kostanyan IA, Lipkin VM. Novel protein haponin regulates cellular response to oxidative stress. Dokl Biochem Biophys. 2011 Sep-Oct;440:225-7. doi: 10.1134/S1607672911050097., Epub 2011 Nov 19. PMID:22095125 doi:http://dx.doi.org/10.1134/S1607672911050097