Structural highlights
Function
GRDC_RHIS5 Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:15466039). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:15466039). The reaction is reversible, but equilibrium greatly favors the decarboxylation reaction (PubMed:15466039). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, but does not act on 2,4-dihydroxybenzoate, 2,5-dihydroxybenzoate, 3,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 2-hydroxybenzoate, or 3-hydroxybenzoate. Only resorcinol is carboxylated by the reverse reaction (PubMed:15466039).[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Yoshida M, Fukuhara N, Oikawa T. Thermophilic, reversible gamma-resorcylate decarboxylase from Rhizobium sp. strain MTP-10005: purification, molecular characterization, and expression. J Bacteriol. 2004 Oct;186(20):6855-63. PMID:15466039 doi:10.1128/JB.186.20.6855-6863.2004
