2epa

From Proteopedia

Solution structure of the first and second zf-C2H2 domains from human Krueppel-like factor 10

Structural highlights

2epa is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Ligands:	ZN
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

KLF10_HUMAN Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.^[1]

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Blok LJ, Grossmann ME, Perry JE, Tindall DJ. Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation. Mol Endocrinol. 1995 Nov;9(11):1610-20. PMID:8584037

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 References

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PDB ID 2epa

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2epa

From Proteopedia

Solution structure of the first and second zf-C2H2 domains from human Krueppel-like factor 10

Structural highlights

Function

Evolutionary Conservation

References

Contents

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