2jr7
From Proteopedia
Jump to: navigation, search
proteopedia linkproteopedia linkSolution structure of human DESR1
Structural highlights
FunctionDPH3_HUMAN Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (By similarity).[1] [2] Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.[3] [4] Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
|
Retrieved from "http://proteopedia.org/wiki/index.php/2jr7"
Categories: Homo sapiens | Large Structures | Shi Y | Wu F | Wu J