2mdk
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proteopedia linkproteopedia linkNMR Solution Structure of MSP-P56S Domain/VAPB in DPC
Structural highlights
DiseaseVAPB_HUMAN Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. FunctionVAPB_HUMAN Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.[1] [2] [3] See AlsoReferences
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Categories: Homo sapiens | Large Structures | Lim L | Qin H | Song J