3juv, resolution 3.12Å
[CP51A_HUMAN] Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
CheckConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Categories: Homo sapiens | Sterol 14-demethylase | Arrowsmith, C H | Bountra, C | Edwards, A M | MacKenzie, F | Park, H | Structural genomic | Strushkevich, N | Usanov, S A | Weigelt, J | Cholesterol biosynthesis | Cytochrome p450 | Endoplasmic reticulum | Heme | Iron | Lipid synthesis | Membrane | Metal-binding | Microsome | Monooxygenase | Nadp | Oxidoreductase | Sgc | Steroid biosynthesis | Sterol 14alpha-demethylase | Sterol biosynthesis | Transmembrane