3vi6

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Crystal Structure of human ribosomal protein L30e

Structural highlights

3vi6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.59Å
Ligands:FMT
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RL30_HUMAN

Publication Abstract from PubMed

Many functions have been reported for the eukaryotic ribosomal protein L30e. L30e makes several inter-subunit and intra-subunit interactions with protein or RNA components of the 80S ribosome. Yeast L30e has been shown to bind to its own transcript to autoregulate expression at both the transcriptional and the translational levels. Furthermore, it has been reported that mammalian L30e is a component of the selenocysteine-incorporation machinery by binding to the selenocysteine-insertion sequence on mRNA. As high-resolution crystal structures of mammalian L30e are not available, the purification, crystallization and X-ray structure analysis of human L30e are presented here.

Crystallization and preliminary X-ray structure analysis of human ribosomal protein L30e.,Kawaguchi A, Ose T, Yao M, Tanaka I Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt, 12):1516-8. Epub 2011 Nov 30. PMID:22139155[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Kawaguchi A, Ose T, Yao M, Tanaka I. Crystallization and preliminary X-ray structure analysis of human ribosomal protein L30e. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt, 12):1516-8. Epub 2011 Nov 30. PMID:22139155 doi:http://dx.doi.org/10.1107/S1744309111045131

Contents


PDB ID 3vi6

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