4fch

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Crystal Structure SusE from Bacteroides thetaiotaomicron with maltoheptaose

Structural highlights

4fch is a 2 chain structure with sequence from Bacteroides thetaiotaomicron VPI-5482. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Ligands:EDO, GLC, SO4
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SUSE_BACTN Starch-binding protein present at the surface of the cell. Mediates starch-binding before starch transport in the periplasm for degradation. SusE and SusF do not constitute the major starch-binding proteins in starch degradation pathway. Has higher affinity for starch compared to SusF.[1] [2] [3]

References

  1. ↑ Shipman JA, Berleman JE, Salyers AA. Characterization of four outer membrane proteins involved in binding starch to the cell surface of Bacteroides thetaiotaomicron. J Bacteriol. 2000 Oct;182(19):5365-72. PMID:10986238
  2. ↑ Cho KH, Salyers AA. Biochemical analysis of interactions between outer membrane proteins that contribute to starch utilization by Bacteroides thetaiotaomicron. J Bacteriol. 2001 Dec;183(24):7224-30. PMID:11717282
  3. ↑ Cameron EA, Maynard MA, Smith CJ, Smith TJ, Koropatkin NM, Martens EC. Multi-domain carbohydrate-binding proteins involved in Bacteroides thetaiotaomicron starch metabolism. J Biol Chem. 2012 Aug 21. PMID:22910908 doi:http://dx.doi.org/10.1074/jbc.M112.397380

Contents


PDB ID 4fch

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