4wig

Structural highlights

Function

CDD_MYCTU Recycles cytidine and 2-deoxycytidine for uridine and 2-deoxyuridine synthesis, respectively. Catalyzes the hydrolytic deamination of cytidine and 2-deoxycytidine to form, respectively, uridine and 2-deoxyuridine.^[1]

See Also

• Deaminase 3D structures

References

1. ↑ Sanchez-Quitian ZA, Schneider CZ, Ducati RG, de Azevedo WF Jr, Bloch C Jr, Basso LA, Santos DS. Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase. J Struct Biol. 2010 Mar;169(3):413-23. Epub 2009 Dec 24. PMID:20035876 doi:10.1016/j.jsb.2009.12.019