Structural highlights
5e2d is a 1 chain structure with sequence from Equus caballus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.87Å |
| Ligands: | , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
FRIL_HORSE Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Publication Abstract from PubMed
Natural protein-based microcompartments containing multiple enzymes promote cascade reactions within cells. We use the apo-ferritin protein cage to mimic such biocompartments by immobilizing two organometallic Ir and Pd complexes into the single protein cage. Precise locations of the metals and their accumulation mechanism were studied by X-ray crystallography.
Immobilization of two organometallic complexes into a single cage to construct protein-based microcompartments.,Maity B, Fukumori K, Abe S, Ueno T Chem Commun (Camb). 2016 Apr 7;52(31):5463-6. doi: 10.1039/c6cc00679e. PMID:27021005[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Maity B, Fukumori K, Abe S, Ueno T. Immobilization of two organometallic complexes into a single cage to construct protein-based microcompartments. Chem Commun (Camb). 2016 Apr 7;52(31):5463-6. doi: 10.1039/c6cc00679e. PMID:27021005 doi:http://dx.doi.org/10.1039/c6cc00679e
