6-aminohexanoate-dimer hydrolase

From Proteopedia

Jump to: navigation, search

Structure of 6-aminohexanoate-dimer hydrolase complex with 6-aminohexanoate (PDB code 2zm9).


  1. Negoro S, Shibata N, Tanaka Y, Yasuhira K, Shibata H, Hashimoto H, Lee YH, Oshima S, Santa R, Oshima S, Mochiji K, Goto Y, Ikegami T, Nagai K, Kato D, Takeo M, Higuchi Y. Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis. J Biol Chem. 2012 Feb 10;287(7):5079-90. doi: 10.1074/jbc.M111.321992. Epub 2011 , Dec 19. PMID:22187439 doi:http://dx.doi.org/10.1074/jbc.M111.321992
  2. Ohki T, Shibata N, Higuchi Y, Kawashima Y, Takeo M, Kato D, Negoro S. Two alternative modes for optimizing nylon-6 byproduct hydrolytic activity from a carboxylesterase with a beta-lactamase fold: X-ray crystallographic analysis of directly evolved 6-aminohexanoate-dimer hydrolase. Protein Sci. 2009 Aug;18(8):1662-73. PMID:19521995 doi:10.1002/pro.185

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

Personal tools