8zwa

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HopBY induced At EDS1-PAD4-ADR1 heterotrimer

Structural highlights

8zwa is a 3 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.48Å
Ligands:RIA
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ADR1_ARATH Disease resistance (R) protein that mediates resistance against Hyaloperonospora parasitica in a salicylic acid-dependent manner. Also mediates resistance against Erysiphe cichoracearum is both salicylic acid-dependent and partially NPR1-dependent. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.[1]

References

  1. Grant JJ, Chini A, Basu D, Loake GJ. Targeted activation tagging of the Arabidopsis NBS-LRR gene, ADR1, conveys resistance to virulent pathogens. Mol Plant Microbe Interact. 2003 Aug;16(8):669-80. PMID:12906111 doi:10.1094/MPMI.2003.16.8.669

Contents


PDB ID 8zwa

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