A-kinase anchor protein

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Human AKAP18 helix (deepskyblue) complex with a dimer of cAMP-dependent protein kinase regulatory subunit (magenta and green) and Cd+2 ions (PDB code 4zp3)

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References

  1. Edwards AS, Scott JD. A-kinase anchoring proteins: protein kinase A and beyond. Curr Opin Cell Biol. 2000 Apr;12(2):217-21. PMID:10712918
  2. Carr DW, Newell AE. The role of A-kinase anchoring proteins (AKaps) in regulating sperm function. Soc Reprod Fertil Suppl. 2007;63:135-41. PMID:17566268
  3. Diviani D, Dodge-Kafka KL, Li J, Kapiloff MS. A-kinase anchoring proteins: scaffolding proteins in the heart. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1742-53. doi:, 10.1152/ajpheart.00569.2011. Epub 2011 Aug 19. PMID:21856912 doi:http://dx.doi.org/10.1152/ajpheart.00569.2011
  4. Gotz F, Roske Y, Schulz MS, Autenrieth K, Bertinetti D, Faelber K, Zuhlke K, Kreuchwig A, Kennedy E, Krause G, Daumke O, Herberg FW, Heinemann U, Klussmann E. AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem J. 2016 Apr 21. pii: BCJ20160242. PMID:27102985 doi:http://dx.doi.org/10.1042/BCJ20160242

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