Aspirin effects on COX aka PGHS

From Proteopedia

Jump to: navigation, search

ASPIRIN'S ANTI-INFLAMMATORY EFFECTS UPON PROSTAGLANDIN H2 SYNTHASE (CYCLOOXYGENASE)

About this Structure

1PTH is a 2 chains structure of sequences from Ovis aries. The May 2001 RCSB PDB Molecule of the Monthby David S. Goodsell features Cyclooxygenase. [1]. Full crystallographic information is available from OCA.

References

<
  1. http://www.bellaonline.com/articles/art8190.asp
  2. Quinque Mayer R, Mayer M. Mayer R, Mayer M. Biological salicyltherapy with cortex salicus [Weidenrinde]. Pharmazie 1949;4:77-81.
  3. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. PMID:5284360
  4. http://nobelprize.org/nobel_prizes/medicine/laureates/1982/vane-lecture.html
  5. Roth GJ, Stanford N, Majerus PW. Acetylation of prostaglandin synthase by aspirin. Proc Natl Acad Sci U S A. 1975 Aug;72(8):3073-6. PMID:810797

Proteopedia Page Contributors and Editors (what is this?)

Ann Taylor, Michal Harel

Personal tools