CRISPR subtype I-B

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Cas6 complex with RNA/DNA hybrid (PDB code 4z7k)

References

  1. Shao Y, Richter H, Sun S, Sharma K, Urlaub H, Randau L, Li H. A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6. Structure. 2016 Apr 5;24(4):547-554. doi: 10.1016/j.str.2016.02.009. Epub 2016, Mar 17. PMID:26996962 doi:http://dx.doi.org/10.1016/j.str.2016.02.009
  2. Niewoehner O, Jinek M, Doudna JA. Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases. Nucleic Acids Res. 2013 Oct 22. PMID:24150936 doi:http://dx.doi.org/10.1093/nar/gkt922

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Alexander Berchansky, Michal Harel

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