Function
D-xylose isomerase (DXI) catalyzes the conversion of D-xylose (DX) to D-xylitol. DXI is part of the fructose and mannose metabolism pathways. Sorbitol is a competitive inhibitor of DXI. DXI is a metal-ion activated tetramer.[1]
Relevance
DXI is used commercially in the production of high fructose corn syrup.
Structural highlights
from Arthrobacter sp is homotetramer. DXI active site contains and the (water molecules shown as red spheres).[2]
3D structures of D-xylose isomerase
D-xylose isomerase 3D structures
