FK506 binding protein

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Wheat FKBP506 domains. Domain 1 (purple), 2 (cyan), 3 (magenta). 3jym

3D Structures of FKBP

Updated on 27-May-2018

  • SlyD

See Peptidyl-prolyl cis-trans isomerase


  1. Kang CB, Hong Y, Dhe-Paganon S, Yoon HS. FKBP family proteins: immunophilins with versatile biological functions. Neurosignals. 2008;16(4):318-25. doi: 10.1159/000123041. Epub 2008 Jul 18. PMID:18635947 doi:
  2. Mayer AD, Dmitrewski J, Squifflet JP, Besse T, Grabensee B, Klein B, Eigler FW, Heemann U, Pichlmayr R, Behrend M, Vanrenterghem Y, Donck J, van Hooff J, Christiaans M, Morales JM, Andres A, Johnson RW, Short C, Buchholz B, Rehmert N, Land W, Schleibner S, Forsythe JL, Talbot D, Pohanka E, et al.. Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group. Transplantation. 1997 Aug 15;64(3):436-43. PMID:9275110
  3. Unger T, Dym O, Albeck S, Jacobovitch Y, Bernehim R, Marom D, Pisanty O, Breiman A. Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain. J Struct Funct Genomics. 2010 Jun;11(2):113-23. Epub 2010 Mar 20. PMID:20306145 doi:10.1007/s10969-010-9085-8
  4. Cheng T, Li H, Xia W, Sun H. Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation. J Biol Inorg Chem. 2011 Nov 2. PMID:22045417 doi:10.1007/s00775-011-0855-y

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