Fasciculin

From Proteopedia

Fasciculins (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations[1] . For toxins in Proteopedia see Toxins.

spinqualitylabelsall models Structure of Fasciculin 1 (PDB entry 1fas) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of Fasciculin

Updated on 20-October-2017

Fasciculin

1fas – FAS1

1fsc - FAS2

FAS+ AChE

2x8b, 1b41, 4ey8, 4bdt – FAS2+hAChE – human

1f8u - FAS2+hAChE (mutant)

1ku6, 1mah - FAS2+mAChE – mouse

1fss - FAS2+AChE – Torpedo californica

References

1. ↑ Karlsson E, Mbugua PM, Rodriguez-Ithurralde D. Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps. J Physiol (Paris). 1984;79(4):232-40. PMID:6530667