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Forkhead box protein

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Human FoxO1 complex with DNA, Ca+2 and chloride ions, 3co6
Ligands: ,
Gene: FOXO1, FKHR, FOXO1A (Homo sapiens)
Related: 3co7, 3coa
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


Forkhead box proteins (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see

See also Transcription and RNA Processing and Neurodevelopmental Disorders.

Contents

3D structures of FOX

Updated on 04-April-2013

FOXO1

3co6, 3coa – hFOXO1 + DNA – human

FOXO3

2uzk – hFOXO3 DNA-binding domain + DNA

FOXO4

3l2c – hFOXO4 DNA-binding domain + DNA

FOXP1

2kiu – hFOXP1 DNA-binding domain (mutant) - NMR

FOXP2

2a07 – hFOXP2 + DNA
2as5 – hFOXP2 DNA-binding domain + nuclear factor of activated T-cell + DNA

FOXP3

3qrf – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA

FOXK2

2c6y – hFOXK2 DNA-binding domain + DNA

FOXK1

2a3s, 2d2w – FOXK1 DNA-binding domain – mouse – NMR

FOXM1

3g73 – hFOXM1 DNA-binding domain + DNA

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Michal Harel, David Canner, Alexander Berchansky

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