Human Acetylcholinesterase

From Proteopedia

Jump to: navigation, search

Structure of human AChE (PDB code 4ey4)

References, for further information on Acetylcholinesterase

  1. Ollis DL, Cheah E, Cygler M, Dijkstra B, Frolow F, Franken SM, Harel M, Remington SJ, Silman I, Schrag J, et al.. The alpha/beta hydrolase fold. Protein Eng. 1992 Apr;5(3):197-211. PMID:1409539
  2. Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, Fleishman SJ. Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Mol Cell. 2016 Jul 21;63(2):337-346. doi: 10.1016/j.molcel.2016.06.012. Epub 2016, Jul 14. PMID:27425410 doi:http://dx.doi.org/10.1016/j.molcel.2016.06.012

To the structures used here:

- Li W, Mak M, Jiang H, Wang Q, Pang Y, Chen K & Han Y (2009) "Novel anti-Alzheimer's dimer Bis(7)-cognitin: cellular and molecular mechanisms of neuroprotection through multiple targets", Neurotherapeutics, vol.6, p.187-201.

- Zhang D & McCammon JA (2005) "The association of tetrameric acetylcholinesterase with colQ tail: a block normal mode analysis", PLoS Comput Biology, vol.1, p.484-491.

To the active site of acetylcholinesterase

- Rosenberry TL (2009) "Strategies to resolve the catalytic mechanism of acetylcholinesterase", Journal of Molecular Neuroscience.

- Currently (November 05, 2009), part of the content of this page is inspired from a source: http://www.biochimie.univ-montp2.fr/licence/enzymo/ache/ache.htm



Hélène ERASIMUS, Blandine FAUVEL, Tiphaine Jaeg 17:08, 12 November 2009 (IST)

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Joel L. Sussman

Personal tools