Pyruvate Kinase

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Human pyruvate kinase tetramer complex with fructose diphosphate, phosphoglycolic acid, Mn+2 and K+ (purple) ions (PDB code 2vgb)

3D structures of pyruvate kinase

Updated on 30-August-2018



Additional Resources

For additional information, see: Carbohydrate Metabolism

References

  1. Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. 3rd ed. Hoboken, NJ: John Wiley & Sons, Inc., 2008, 501-503.
  2. authors, The scop. "Structural Classification of Proteins". 2009. 2/26 2010. <http://scop.berkeley.edu/data/scop.b.c.jh.b.b.d.html>.
  3. authors, The scop. "Structural Classification of Proteins". 2009. 2/26 2010. <http://scop.berkeley.edu/data/scop.b.c.jh.b.b.d.html>.
  4. Robergs, Robert. "Exercise-Induced Metabolic Acidosis: Where do the Protons come from?". 2009. 2/27 2010. <http://www.sportsci.org/jour/0102/rar.htm>.
  5. Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. 3rd ed. Hoboken, NJ: John Wiley & Sons, Inc., 2008, 501-503.
  6. Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. 3rd ed. Hoboken, NJ: John Wiley & Sons, Inc., 2008, 501-503.
  7. Dann LG, Britton HG. Kinetics and mechanism of action of muscle pyruvate kinase. Biochem J. 1978 Jan 1;169(1):39-54. PMID:629752
  8. Mattevi A, Bolognesi M, Valentini G. The allosteric regulation of pyruvate kinase. FEBS Lett. 1996 Jun 24;389(1):15-9. PMID:8682196
  9. Jurica MS, Mesecar A, Heath PJ, Shi W, Nowak T, Stoddard BL. The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate. Structure. 1998 Feb 15;6(2):195-210. PMID:9519410
  10. Oria-Hernandez J, Cabrera N, Perez-Montfort R, Ramirez-Silva L. Pyruvate kinase revisited: the activating effect of K+. J Biol Chem. 2005 Nov 11;280(45):37924-9. Epub 2005 Sep 7. PMID:16147999 doi:10.1074/jbc.M508490200
  11. Dann LG, Britton HG. Kinetics and mechanism of action of muscle pyruvate kinase. Biochem J. 1978 Jan 1;169(1):39-54. PMID:629752
  12. Oria-Hernandez J, Cabrera N, Perez-Montfort R, Ramirez-Silva L. Pyruvate kinase revisited: the activating effect of K+. J Biol Chem. 2005 Nov 11;280(45):37924-9. Epub 2005 Sep 7. PMID:16147999 doi:10.1074/jbc.M508490200
  13. Zanella A, Fermo E, Bianchi P, Chiarelli LR, Valentini G. Pyruvate kinase deficiency: the genotype-phenotype association. Blood Rev. 2007 Jul;21(4):217-31. Epub 2007 Mar 13. PMID:17360088 doi:10.1016/j.blre.2007.01.001

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