Malate dehydrogenase

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Malate dehydrogenase complex with NAD, sulfate and Na+ ion (purple) (PDB code 2x0i)


3D Structures of Malate Dehydrogenase

Updated on 22-January-2019
The holo-MDH contains NAD or its derivatives while the apo-MDH lacks it.

Additional Resources


References

  1. Minarik P, Tomaskova N, Kollarova M, Antalik M. Malate dehydrogenases--structure and function. Gen Physiol Biophys. 2002 Sep;21(3):257-65. PMID:12537350
  2. Matsuda T, Takahashi-Yanaga F, Yoshihara T, Maenaka K, Watanabe Y, Miwa Y, Morimoto S, Kubohara Y, Hirata M, Sasaguri T. Dictyostelium Differentiation-Inducing Factor-1 Binds to Mitochondrial Malate Dehydrogenase and Inhibits Its Activity. J Pharmacol Sci. 2010 Feb 20. PMID:20173310
  3. Matsuda T, Takahashi-Yanaga F, Yoshihara T, Maenaka K, Watanabe Y, Miwa Y, Morimoto S, Kubohara Y, Hirata M, Sasaguri T. Dictyostelium Differentiation-Inducing Factor-1 Binds to Mitochondrial Malate Dehydrogenase and Inhibits Its Activity. J Pharmacol Sci. 2010 Feb 20. PMID:20173310
  4. Musrati RA, Kollarova M, Mernik N, Mikulasova D. Malate dehydrogenase: distribution, function and properties. Gen Physiol Biophys. 1998 Sep;17(3):193-210. PMID:9834842
  5. Boernke WE, Millard CS, Stevens PW, Kakar SN, Stevens FJ, Donnelly MI. Stringency of substrate specificity of Escherichia coli malate dehydrogenase. Arch Biochem Biophys. 1995 Sep 10;322(1):43-52. PMID:7574693 doi:http://dx.doi.org/10.1006/abbi.1995.1434
  6. Plancarte A, Nava G, Mendoza-Hernandez G. Purification, properties, and kinetic studies of cytoplasmic malate dehydrogenase from Taenia solium cysticerci. Parasitol Res. 2009 Jul;105(1):175-83. Epub 2009 Mar 10. PMID:19277715 doi:10.1007/s00436-009-1380-6
  7. Goward CR, Nicholls DJ. Malate dehydrogenase: a model for structure, evolution, and catalysis. Protein Sci. 1994 Oct;3(10):1883-8. PMID:7849603 doi:http://dx.doi.org/10.1002/pro.5560031027

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