Methotrexate

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References

  1. Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx
  2. Medical Pharmacology Topics. (n.d.). Angelfire: Welcome to Angelfire. Retrieved March 10, 2011, from http://www.angelfire.com/sc3/toxchick/medpharm/medpharm65.html
  3. Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx
  4. Schnell JR, Dyson HJ, Wright PE (June 2004). "Structure, dynamics, and catalytic function of dihydrofolate reductase.". Annual Review of Biophysics and Biomolecular Structure 33: 119–40
  5. DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE. (n.d.). RCSB Protein Database. Retrieved March 10, 2011, from www.rcsb.org/pdb/results
  6. DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE. (n.d.). RCSB Protein Database. Retrieved March 10, 2011, from www.rcsb.org/pdb/results
  7. DNA Synthesis - Replication: Chromatin Structure. (n.d.). The Medical Biochemistry Page. Retrieved March 10, 2011, from http://themedicalbiochemistrypage.org/dna.html
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  9. Rajagopalan, P. T. Ravi; Zhang, Zhiquan; McCourt, Lynn (2002). "Interaction of dihydrofolate reductase with methotrexate: Ensemble and single-molecule kinetics". Proceedings of the National Academy of Sciences 99 (21): 13481–6.
  10. Methotrexate and Folic Acid. (2006, September 3). Wikimedia Commons. Retrieved March 10, 2011, from commons.wikimedia.org/.png
  11. Enzymes. (n.d.). Oregon State University. Retrieved March 10, 2011, from http://oregonstate.edu/instruction/bb450/fall2010/lecture/enzymesoutline.html
  12. Volpato, J., Yachnin, B., & Blanchet, J. (2009). Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.. Journal Biol. Chem., 284, 20079-20089.
  13. DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE. (n.d.). RCSB Protein Database. Retrieved March 10, 2011, from www.rcsb.org/pdb/results
  14. Methotrexate Information from Drugs.com. (n.d.). Drugs.com | Prescription Drugs - Information, Interactions & Side Effects. Retrieved March 10, 2011, from http://www.drugs.com/methotrexate.html
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  17. Schwartza, S., & Borner, K. (2007). Glucarpidase (Carboxypeptidase G2) Intervention in Adult and Elderly Cancer Patients with Renal Dysfunction and Delayed Methotrexate Elimination After High-Dose Methotrexate Therapy. The Oncologist, 12(11), 1299-1308.
  18. Sirotnak, F., Dorick, D., & Moccio, D. (1978). Murine Tumor ModelsRescue Therapy in the L1210 Leukemia and Sarcoma 180 Optimization of High-Dose Methotrexate with Leucovorin . CANCER RESEARCH, 38, 345-353. Retrieved March 10, 2011, from cancerres.aacrjournals.org/content/38/2/345.full.pdf
  19. Methotrexate. (2010, September 1). CCO Formulary. Retrieved March 10, 2011, from www.cancercare.on.ca/pdfdrugs/methotre.pdf

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