NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol

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NADPH dehydrogenase complex with FAD and dicoumarol 2f1o

3D structures of NQ01

Quinone reductase


Additional Resources

For additional information, see: Carbohydrate Metabolism

References

  • Faig M, Bianchet MA, Talalay P, Chen S, Winski S, Ross D, Amzel LM. Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3177-82. PMID:10706635 doi:http://dx.doi.org/10.1073/pnas.050585797
  • Asher G, Dym O, Tsvetkov P, Adler J, Shaul Y. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry. 2006 May 23;45(20):6372-8. PMID:16700548 doi:10.1021/bi0600087

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Orly Dym, Michal Harel, Jaime Prilusky, Moshe Ben-David, Joel L. Sussman, David Canner, Eric Martz

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