Receptor for activated protein kinase C 1

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Human receptor for activated protein kinase C 1 complex with glycerol (PDB code 4aow)

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3D sructures of receptor for activated protein kinase C 1

References

  1. Vomastek T, Iwanicki MP, Schaeffer HJ, Tarcsafalvi A, Parsons JT, Weber MJ. RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility. Mol Cell Biol. 2007 Dec;27(23):8296-305. Epub 2007 Oct 1. PMID:17908799 doi:http://dx.doi.org/10.1128/MCB.00598-07
  2. Chang BY, Conroy KB, Machleder EM, Cartwright CA. RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells. Mol Cell Biol. 1998 Jun;18(6):3245-56. PMID:9584165
  3. Nilsson J, Sengupta J, Frank J, Nissen P. Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. EMBO Rep. 2004 Dec;5(12):1137-41. PMID:15577927 doi:http://dx.doi.org/10.1038/sj.embor.7400291
  4. Berns H, Humar R, Hengerer B, Kiefer FN, Battegay EJ. RACK1 is up-regulated in angiogenesis and human carcinomas. FASEB J. 2000 Dec;14(15):2549-58. PMID:11099474 doi:http://dx.doi.org/10.1096/fj.99-1038com
  5. Lin W, Zhang Z, Xu Z, Wang B, Li X, Cao H, Wang Y, Zheng SJ. The association of receptor of activated protein kinase C 1(RACK1) with infectious bursal disease virus viral protein VP5 and voltage-dependent anion channel 2 (VDAC2) inhibits apoptosis and enhances viral replication. J Biol Chem. 2015 Mar 27;290(13):8500-10. doi: 10.1074/jbc.M114.585687. Epub 2015, Jan 12. PMID:25583988 doi:http://dx.doi.org/10.1074/jbc.M114.585687

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