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Ribosomal protein L6
From Proteopedia
Ribosomal protein L6 (RPL6) is one of the 34 proteins which belong to the of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is known to bind to the 5S RRNA from the large subunit. It is located in the aminoacyl-tRNA binding site of the peptidyltransferase center. In the archaea like in Haloarcula marismortui the L6 is called L6P (RPL6P). The images at the left and at the right correspond to one representative RPL6, i.e. the crystal structure of Ribosomal protein L6 from Thermus thermophilus (2xg0, chain H).
3D Structures of Ribosomal protein L6
Updated on 06-March-2013
RPL6
1rl6 – RPL6 – Geobacillus stearothermophilus
L6 in 50S subunit+RNA
2xg0, 2xg2, 3kir, 3kit, 3kiw, 3kiy – TtRPL6 in 50S subunit+RNA fragments - Thermus thermophilus
2x9s, 2x9u, 3kni, 3knk, 3knm, 3kno, 2wrj, 2wrl, 2wro, 2wrr, 3hux, 3huz, 2wh2, 2wh4, 2wdi, 2wdj, 2wdl, 2wdn, 1vsp, 2v47, 2v49, 1vsa, 2hgj, 2hgq, 2hgu, 2j01, 2j03, 1yl3, 3mrz, 3ms1, 3i8f, 3i8i, 3i9c, 3i9e, 3f1f, 3f1h, 3d5b, 3d5d, 2b66, 2b9n, 2b9p, 1giy, 2xqe, 2y0v, 2y0x, 2y0z, 2y11, 2y13, 2y15, 2y17, 2y19, 3pyo, 3pyr, 3pyt, 3pyv, 3tve, 3tvh, 3uye, 3uyg, 3uz1, 3uz2, 3uz8, 3uz9, 3uzf, 3uzh, 3uzk, 3uzn, 4dha, 4dhc, 3v23, 3v25, 3v27, 3v29, 3v2d, 3v2f, 3zvp - TtRPL6 in 50S subunit+5S RRNA+23S RRNA
3fin - TtRPL6 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
2wwq – EcRPL6 in 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA – Escherichia coli
3i1n, 3i1p, 3i1r, 3i1t, 3i20, 3i22, 3e1b, 3e1d, 3df2, 3df4, 2vhn, 2qov, 2qox, 2i2t, 2i2v, 1vs6, 1vs8, 2aw4, 2awb, 3ofd, 3og0, 1vor, 1vou, 1vow, 1voy, 1vp0, 1pnu, 1pny, 3r8s, 3r8t, 3uos, 3uxq, 3uxr, 3sgf, 4gar, 4gau - EcRPL6 in 50S subunit+5S RRNA+23S RRNA
3fik, 2gya, 2gyc, 3bbx, 1p85, 1p86, 3izt, 3izu, 3j0t, 3j0w, 3j0y, 3j11, 3j12, 3j14, 3j19 - EcRPL6 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
3kcr - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+preprotein translocase
3j01 – EcRPL6 in 50S subunit+5S RRNA+23S RRNA+preprotein translocase – Cryo-EM
2rdo - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM
3bbo - RPL6 in 50S subunit+5S RRNA+23S RRNA+4.8S RRNA – Cryo-EM – spinach
2zjq, 2zjr, 1nkw - DrRPL6 in 50S subunit+5S RRNA+23S RRNA – Deinococcus radiodurans
1kqs, 1qvg - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+CCA - Haloarcula marismortui
1jj2, 1ffk, 3cc2, 2qa4, 1s72 - HmRPL6P in 50S subunit+5S RRNA+23S RRNA
3cc7, 3cce, 3ccj, 3ccl, 3ccm, 3ccq, 3ccr, 3ccs, 3ccu, 3ccv - HmRPL6P in 50S subunit+5S RRNA+23S RRNA (mutant)
1yj9 - HmRPL6P in 50S subunit (L22 mutant)+5S RRNA+23S RRNA
1vq4, 1vq5, 1vq7, 1vql, 1vqm, 1vqp - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+transition state analog
1vq6, 1vqk, 1vqn - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+ c-hpmn+CCA-Phe-caproic acid-biotin
1q86 - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+CCA-Phe-caproic acid-biotin
1vqo - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+ CCPMN
1qvf - HmRPL6P in 50S subunit+5S RRNA+23S RRNA + deacylated tRNA minihelix
3j21 - RPL6 in 50S subunit – Cryo-EM – Pyrococcus furiosus
L6 in 50S subunit + antibiotics
3dll, 2zjp, 3cf5, 1xbp, 1sm1, 1nwx, 1nwy, 3pio, 3pip - DrRPL6 in 50S subunit+5S RRNA+23S RRNA+antibiotic
2ogm, 2ogn, 2ogo - DrRPL6+23S RRNA+pleuromutilin derivative
3oh5, 3oh7, 3ohj, 3ohk, 3ohz, 3oi1, 3oi3, 3oi5 – TtRPL6 in 50S subunit+5S RRNA+23S RRNA+antibiotic
2qam, 2qao, 2qba, 2qbc, 2qoz, 2qp1, 3ofc, 3ofz, 3ofq, 3ofr, 1vt2, 3orb, 3oas, 3oat - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+antibiotic
1k73, 1kc8, 1k8a, 1k9m, 1kd1, 1m1k, 3i55, 3i56, 3g4s, 3g6e, 3g71, 2qex, 3cpw, 3cc4, 3cd6, 2otj, 2otl, 1yit, 1q7y, 1q81, 1q82, 1n8r, 1nji, 3cxc - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+antibiotic - Halobacterium marismortui
1yhq, 1yi2, 1yij, 1yjn, 1yjw - HmRPL6P in 50S subunit+5S RRNA+23S RRNA (mutant)+antibiotic
1m90, 3cma, 3cme, 1vq8, 1vq9 - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+ sparsomycin+CCA-Phe-caproic acid-biotin
L6 in large 60S ribosomal subunit
3o58, 3o5h – yRPL6 in 60S subunit+25S RRNA+5SRRNA+5.8RRNA
3izr – RPL6 in 60S subunit – wheat – Cryo-EM
1s1i – yRPL6 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast
3izs – yRPL6 in 60S ribosomal subunit – Cryo-EM
3u5e, 3u5i – yRPL6 in 60S ribosomal subunit
4b6a - yRPL6 in 60S ribosomal subunit + P0 + P1 + P2 + ARX1 – Cryo-EM
3j16 - yRPL6 + yRPL10 + yRPL11 + yRPS6 + yRPS24 + yRPS30+18S RRNA + 28S RRNA + P-site tRNA + RLI1P + DOM34P – Cryo-EM
L6 in large + small ribosomal subunit
1ml5 - EcRPL6 in 50S ribosomal subunit+30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA – EM
L6 in 50S subunit + ribosome releasing factor (RRF)
2qbe, 2qbg, 2qbi, 2qbk, 2z4l, 2z4n - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+RRF
L6 in 50S subunit + various proteins
2vhm - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix
2j28 - EcRPL6 in 50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM
1w2b - HmRPL6P in 50S subunit+5S RRNA+23S RRNA+trigger factor N-terminal
L6 in part of 50S subunit
1c04 – HmRPL6P+RPL2+RPL11+RPL14+23S RRNA fragment
1eg0 – EcRPL6+RPL1+RPL11+RPS4+RPS5+RPS6+RPS7+RPS8+RPS15+RPS17+RPS20+fMet-tRNA+23S RRNA fragment – Cryo-EM
487d – RPL6+RPL1+RPL2+RPL9+RPL11+RPL14+RPL25 – Cryo-EM
