Serotonin N-acetyltransferase

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Serotonin N-acetyltransferase 1cjw

3D structures of serotonin N-acetyltransferase

Updated on 25-May-2017

1b6b – sSNA – sheep

1cjw – sSNA + CoA S-acetyl tryptamine

1kuv - sSNA (mutant) + CoA S-acetyl bromotryptamine

1kux - sSNA (mutant) + CoA S-trimethylene-acetyl tryptamine

1kuy, 1l0c - sSNA (mutant) + CoA S-acetyl tryptamine

1ib1 – sSNA + protein kinase C inhibitor protein-1

See Also


References

  1. 1.0 1.1 Hickman AB, Namboodiri MA, Klein DC, Dyda F. The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog. Cell. 1999 Apr 30;97(3):361-9. PMID:10319816
  2. Hickman AB, Klein DC, Dyda F. Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism. Mol Cell. 1999 Jan;3(1):23-32. PMID:10024876
  3. Zheng W, Cole PA. Serotonin N-acetyltransferase: mechanism and inhibition. Curr Med Chem. 2002 Jun;9(12):1187-99. PMID:12052171

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