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- Image:E2020 interactins in AChE gorge.jpg (93 bytes)
1: E2020 interacting with AChE active-stie gorge, Fig5: Kryger et al (1999) Stru... - Ache (34 bytes)
- AChE inhibitors and substrates (53,646 bytes)
3: ==AChE substrate==
5: ...do californica''] [[acetylcholinesterase]] (''Tc''AChE) in 1991 <ref name="Sussman">PMID:1678899</ref> o...
7: ...d (Ser200, His440, and Glu327)</scene> (ACh/''Tc''AChE structure [[2ace]]). The residues <scene name='2a...
9: ==AChE monovalent inhibitors==
15: ...are potent inhibitors which rapidly phosphonylate AChE and then may undergo an internal dealkylation rea... - Category:Torpedo ache (43 bytes)
1: List of pages with the keyword Torpedo ache - Category:Ache (35 bytes)
1: List of pages with the keyword Ache - Image:ACHE.pdb (32 bytes)
- AChE bivalent inhibitors (44 bytes)
1: #REDIRECT [[AChE inhibitors and substrates]] - AChE bivalent inhibitors (Part II) (44 bytes)
1: #REDIRECT [[AChE inhibitors and substrates]] - AChE inhibitors and substrates (Part II) (79 bytes)
1: #REDIRECT [[AChE_inhibitors_and_substrates#Treatment_of_Alzheimer.... - Image:Hydrolyse ACh par AChE.jpg (14 bytes)
- Image:Sites de l'AChE.jpg (11 bytes)
- AChE inhibitors and substrates (Part III) (44 bytes)
1: #REDIRECT [[AChE inhibitors and substrates]] - Sandbox AChE Adv JMol (1,042 bytes)
2: ...on='Caption for this structure' scene='10/1072244/Ache_jmol_adv/1'>
3: This is a default text for your page '''Sandbox AChE Adv JMol'''. Click above on '''edit this page''' ...
8: <scene name='10/1072244/Ache_jmol_adv/1'>like the opening secene</scene> - Sandbox AChE Surface (1,118 bytes)
2: ...on='Caption for this structure' scene='10/1072242/Ache_together_surf_cartoon/1'>
3: This is a default text for your page '''Sandbox AChE Surface'''. Click above on '''edit this page''' t...
8: ...ne name='10/1072242/Ache_together_surf_cartoon/1'>AChE - Surface white, 40% transparent, Cartoon Rainbow... - AChE (33 bytes)
- Treatments:AChE Inhibitor References (307 bytes)
- Image:AChE-Page-Cholinergic-Synapse.jpg (0 bytes)
- Image:AChE-Page-ACh shematic.JPG (0 bytes)
- Image:AChE-Page-schematic-gorge.jpg (0 bytes)
- Image:AChE-Page-schematic-fas.JPG (0 bytes)
Page text matches
- Acetylcholinesterase (8,905 bytes)
1: ...2/22/Ache_with_ach/2' caption='Torpedo california AChE (PDB code [[2ace]])'>
3: ...) poisons is attributed primarily to their potent AChE inhibitors.
8: ...do californica''] [[acetylcholinesterase]] (''Tc''AChE) in 1991 opened up new horizons in research on an...
13: ...d (Ser200, His440, and Glu327)</scene> (ACh/''Tc''AChE structure [[2ace]]). The residues <scene name='2a...
18: ...e various cholinesterase inhibitors interact with AChE can be see at:<br /> - Sandbox Tst (3,047 bytes)
2: ... Scene ='1som/Ache_soman/1' side='right' caption='AChE complex with soman'>
8: (see also [[AChE inhibitors and substrates]], [[2wfz]], [[2wg0]], ...
11: ...nts is attributed primarily to their being potent AChE inhibitors.
14: ...are potent inhibitors which rapidly phosphonylate AChE and then may undergo an internal dealkylation rea...
18: ...sites of aged sarin-TcAChE ([[1cfj]]) and soman-TcAChE were essentially identical and provided structura... - Acetylcholine (3,078 bytes)
14: ...Ser200, His440, and Glu327)</scene> of (ACh/''Tc''AChE structure [[2ace]]). The residues <scene name='2a... - 2jez (4,464 bytes)
24: ...ystallographic and mass spectrometric analyses of AChE crystals. The results explain the relative reacti... - 2jey (4,362 bytes)
24: ...ystallographic and mass spectrometric analyses of AChE crystals. The results explain the relative reacti... - 2jf0 (4,421 bytes)
24: ...ystallographic and mass spectrometric analyses of AChE crystals. The results explain the relative reacti... - Aricept Complexed with Acetylcholinesterase (4,526 bytes)
2: [[Image:E2020_interactins_in_AChE_gorge.jpg|left|250px]]<br />
4: (see also [[AChE inhibitors and substrates]])
6: ... for AChE, binding to both electric eel and mouse AChE in the nanomolar range.
11: The X-ray structure of the E2020-''Tc''AChE complex shows that E2020 has a <scene name='1eve/...
14: ...ity for AChE and a high degree of selectivity for AChE versus butyrylcholinesterase (BChE). It also deli... - Image:E2020 interactins in AChE gorge.jpg (93 bytes)
1: E2020 interacting with AChE active-stie gorge, Fig5: Kryger et al (1999) Stru... - 2c4h (4,831 bytes)
24: ...e structural insight into substrate inhibition in AChE at two different substrate concentrations. Our st... - 2c0p (4,886 bytes)
24: ...o the conformation found in the apo structure of mAChE. A hydrogen bond between the imidazole ring of Hi... - 2c0q (4,960 bytes)
24: ...o the conformation found in the apo structure of mAChE. A hydrogen bond between the imidazole ring of Hi... - 2c5g (4,315 bytes)
22: ...e structural insight into substrate inhibition in AChE at two different substrate concentrations. Our st... - 2c58 (4,852 bytes)
24: ...e structural insight into substrate inhibition in AChE at two different substrate concentrations. Our st... - 2jgf (5,030 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jgj (5,105 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jgm (4,902 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jgl (5,090 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jgi (4,986 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jgk (4,961 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H... - 2jge (5,038 bytes)
24: ...y similar to the noninhibited apo conformation of AChE. A minor structural change in the side chain of H...
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