TNF receptor-associated factor

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Human TRAF2 TRAF domain (green) complex with TNFR type 1 associated death domain protein TRADD (deepskyblue) (PDB code 1f3v)

3D Structures of TNF receptor-associated factor

Updated on 16-October-2017


  1. Bradley JR, Pober JS. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene. 2001 Oct 1;20(44):6482-91. PMID:11607847 doi:
  2. Hildebrand JM, Yi Z, Buchta CM, Poovassery J, Stunz LL, Bishop GA. Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions. Immunol Rev. 2011 Nov;244(1):55-74. doi: 10.1111/j.1600-065X.2011.01055.x. PMID:22017431 doi:
  3. Arthur JF, Shen Y, Gardiner EE, Coleman L, Murphy D, Kenny D, Andrews RK, Berndt MC. TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets. J Thromb Haemost. 2011 Jan;9(1):163-72. doi: 10.1111/j.1538-7836.2010.04091.x. PMID:20946164 doi:
  4. Park YC, Ye H, Hsia C, Segal D, Rich RL, Liou HC, Myszka DG, Wu H. A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Cell. 2000 Jun 23;101(7):777-87. PMID:10892748

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