User:Carlos Vázquez García/TFG/Parte7

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8. Bibliografía

[1] Pylayeva-Gupta Y., Grabocka E. and Bar-Sagi D. (2011) Ras oncogenes: weaving a tumorigenic web. Nature Reviews Cancer 11, 761-774.

[2] Fernández-Medarde, Santos E., (2011). Ras in Cancer and Developmental Diseases.Genes & Cancer. 2, 344–358.

[3] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 15 Mar. 2016].

[4] Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW. Second-site screening of K-Ras in the presence of covalently attached first-site ligands [En línea] Disponible en:http://www.ebi.ac.uk/pdbe/entry/pdb/4Q03 [Visitado 15 Mar. 2016].

[5] Maurer T., Garrenton L.S., Oh A., Pitts K., Anderson D.J., Skelton N.J., Fauber B.P., Pan B., Malek S., Stokoe D., Ludlam M.J., Bowman K.K., Wu J., Giannetti A.M., Starovasnik M.A., Mellman I., Jackson P.K., Rudolph J., Wang W., Fang G., (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences U.S.A. 109:5299-5304.

[6] Sancho López, P., (2010). Actividad enzimática. [ebook] Alcalá de Henares: Pilar Sáncho López, p.5. Disponible en: http://www3.uah.es/bioquimica/Sancho/farmacia/temas/tema-7_catalisis-enzimatica.pdf [Visitado 16 Mar. 2016].

[7] Bollag, G., Adler, F., elMasry, N., McCabe, P., Conner, E., Thompson, P., McCormick, F. and Shannon, K. (1996). Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. journal of biological chemistry, 271, 32491-32494.

[8] Fletcher. C., (2011). Panitumumab: The KRAS story. [En línea] Disponible en: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2011/11/WC500118101.pdf [Visitado 16 Mar. 2016].

[9] V8rik, 17 January 2009. Basic amino acid condensation. [Imagen] Disponible en: https://commons.wikimedia.org/wiki/File:AminoacidCondensation.svg [Visitado 16 Mar. 2016].

[10] UniProt, (n.d.). K-RAS 2A Sequence. [Imagen] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].

[11] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].

[12] Tong Y, Tempel W, Shen L, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC), (2009). Human K-Ras (Q61H) in complex with a GTP analogue. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/3gft/bound/GNP [Visitado 16 Mar. 2016].

[13] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4m1o/bound/GDP [Visitado 16 Mar. 2016]

[14] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].

[15] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4q03/bound/MG [Visitado 16 Mar. 2016].

[16] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4Q03 [Visitado 16 Mar. 2016].

[17] Oh, A., Maurer, T., Garrenton, L.S., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Ruldolph, J., Fang, G., Wang, W. (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4DSO [Visitado 16 Mar. 2016].

[18] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].

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