User:Michael Strong/TB

From Proteopedia

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Web Supplement to:
Comprehensive Structural Analysis of Drug-Resistant Mutations in Mycobacterium tuberculosis.

Michael Strong ^1,2, Andreas Sandgren ^3,4, James E. Galagan ^5,6, Mark Borowsky ^5,7,8, George M. Church ², Megan B. Murray ³,

1.Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206,
2.Department of Genetics, Harvard Medical School, Boston, MA 02115,
3.Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115,
4.European Centre for Disease Prevention and Control,
5.Broad Institute of MIT and Harvard, Cambridge, MA, 02142,
6.College of Engineering, Boston University, Boston, MA, 02118,
7.Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, 02114,
8.Department of Genetics, Massachusetts General Hospital, Boston, MA, 02114.

Correspondence regarding this webpage can be sent to: StrongM@NJHealth.org

Please click on the GREEN links to see the structural details described.

Contents 1 RpoB homology model with Rifampin bound 2 GidB homology model with S-adenosylmethionine bound 3 RpsL homology model with streptomycin 4 InhA crystal structure with ETH-NAD bound 5 InhA crystal structure with INH-NAD bound 6 GyrA crystal structure 7 KatG crystal structure with heme bound 8 PncA crystal structure

RpoB homology model with Rifampin bound

RpoB Homology Model with Rifampin bound Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

GidB homology model with S-adenosylmethionine bound

GidB homology model with S-adenosylmethionine bound Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

RpsL homology model with streptomycin

RpsL homology model with streptomycin Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

InhA crystal structure with ETH-NAD bound

InhA with ETH-NAD, X-ray Crystal Structure 2h9i Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

InhA crystal structure with INH-NAD bound

InhA with INH-NAD, X-ray Crystal Structure 2nv6 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

GyrA crystal structure

GyrA X-ray Crystal Structure 3ILW Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

KatG crystal structure with heme bound

KatG, X-ray Crystal Structure 2cca Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

PncA crystal structure

PncA, X-ray Crystal Structure 3GBC Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image