Cellobiohydrolase

spinqualitylabelsall models Glycosylated cellobiohydrolase I catalytic domain complex with cellobiose and Cd+2 ions (PDB code 3cel) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Cellobiohydrolase (CBH) is a cellulase which degrades cellulose by hydrolysing the 1,4-β-D-glycosidic bonds. CBH is an exocellulase which cleaves two to four units from the ends of cellulose. There are two types of CBH. CBHI cleaves progressively from the reducing end while CBHII cleaves progressively from the nonreducing end of cellulose.. The exo-acting CBH I is called Cel7A. The endo-acting CBH I is called Cel7B. Cellobiohydrolase Cel6A contains an active site within a tunnel which opens and closes in response to ligand binding. Structural highlights The active site of CBH contains Glu-Asp-Glu (Gln-Asp-Glu in 3cel, cyan) and is situated at the bottom of a tunnel. Water molecules shown as red spheres. 3D structures of cellobiohydrolase Cellobiohydrolase 3D structures

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