1h1k

THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA

spinqualitylabelsall models 1h1k, resolution 10.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1h1k is a 6 chain structure with sequence from Bluetongue virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 10Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff. The core of bluetongue virus binds double-stranded RNA.,Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI J Virol. 2002 Sep;76(18):9533-6. PMID:12186935 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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