2y4y

Structure of a domain from the type IV pilus biogenesis lipoprotein PilP, from Pseudomonas aeruginosa

spinqualitylabelsall models 2y4y, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2y4y is a 4 chain structure with sequence from Pseudomonas aeruginosa PAO1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.7Å Ligands: ACT, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PILP_PSEAE Inner membrane component of the type IV (T4S) secretion system that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility. PilN/PilO heterodimers form the foundation of the inner-membrane PilM/PilN/PilO/PilP complex which plays an essential role in the assembly of a functional T4 pilus (PubMed:19857645). PilP connects PilO to the secretin PilQ. In turn, the PilM/PilN/PilO/PilP/PilQ complex facilitates transit of the pilus through the periplasm and clamps the pilus in the cell envelope (PubMed:23457250).

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