4abz
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TetR(D) in Complex with Tigecycline and Magnesium, co-crystallized
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Structural highlights
FunctionTETR4_ECOLX TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. See AlsoContents | ||||||||||||||||||||
This page was last modified 11:23, 20 December 2023.