5f4m

Protruding domain of GII.17 norovirus Kawasaki323

spinqualitylabelsall models 5f4m, resolution 2.27Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5f4m is a 2 chain structure with sequence from Norovirus 13-BH-1/2013/GII.17. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.27Å Ligands: EDO Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A0A7CJV4_9CALI Publication Abstract from PubMed Recent reports suggest that human GII.17 noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray structural analysis of GII.17 P domains from 2002 to 2014/15 suggested that surface exposed substitutions on the uppermost part of the P domain might have generated a novel 2014/15 GII.17 variant. Structural evolution of the emerging 2014/15 GII.17 noroviruses.,Singh BK, Koromyslova A, Hefele L, Gurth C, Hansman GS J Virol. 2015 Dec 23. pii: JVI.03119-15. PMID:26699640 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Virus coat proteins 3D structures

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