5u72
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Structure of human MR1-5OH-DCF in complex with human MAIT A-F7 TCR
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Structural highlights
FunctionHMR1_HUMAN Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.[1] See AlsoReferences | ||||||||||||||||||||
This page was last modified 13:22, 4 October 2023.