6cpj
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Solution structure of SH3 domain from Shank2
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Structural highlights
FunctionSHAN2_RAT Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.[1] See AlsoReferences | ||||||||||||||||||
This page was last modified 07:30, 1 May 2024.