6ebr

Activation of RR02 bound to BeF3

spinqualitylabelsall models 6ebr, resolution 1.82Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ebr is a 1 chain structure with sequence from Streptococcus pneumoniae TIGR4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.816Å Ligands: BEF, MN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function WALR_STRPN Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism (By similarity). Binds to the promoter region of the transcription factor fabT gene in the fabTH-acp operon in vitro (PubMed:27610104). Inhibits transcription of fabT, probably acting in an unphosphorylated form, thereby playing a role in the regulation of fatty acid biosynthesis (PubMed:15774879, PubMed:27610104). Essential for normal growth in vitro (By similarity). Required for maintaining normal cellular morphology, acting, at least in part, by regulating peptidoglycan hydrolase pcsB (By similarity). Involved in maintaining expression of WalRK regulon genes in exponentially growing cells (By similarity).[UniProtKB:A0A0H2ZN37][UniProtKB:P37478][UniProtKB:Q8DPL7] See Also Response regulator 3D structure

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