6f02
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Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution
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Structural highlights
FunctionKAIN_HUMAN Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.[1] See AlsoReferences | ||||||||||||||||||||
This page was last modified 05:12, 21 November 2024.