6uxz

(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR

spinqualitylabelsall models 6uxz, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6uxz is a 2 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.8Å Ligands: QL4, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GABR_BACSU Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate. See Also Tetracycline repressor protein 3D structures Transcriptional activator 3D structures

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