6yr2

TetR(D) soaked with Tigecycline P4(1)2(1)2

spinqualitylabelsall models 6yr2, resolution 1.95Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6yr2 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.95Å Ligands: CL, MG, SO4, T1C Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TETR4_ECOLX TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. See Also Tetracycline repressor protein 3D structures

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