Arginine kinase

spinqualitylabelsall models Arginine kinase complex with D-arginine (magenta), ADP (crimson), NO3- and Mg+2 ions and (PDB code 1bg0) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Arginine kinase or Protein-arginine kinase (AK) is a phosphagen kinase which catalyzes the conversion of L-arginine and ATP to N-phospho-L-arginine and ADP. AK is part of arginine and proline metabolism. The phosphagen kinase reaction of AK is central to cellular energy homeostasis, i.e. maintenance of ATP level in invertebrates. Another phosphagen kinase found mostly in vertebrates is Creatine Kinase whose substrate is creatine. For more details see Arginine Kinase AK. Relevance High levels of Arg are found in plasma of patients with chronic hemolytic anemia. Structural highlights The active site of AK is located between its N-terminal helical region and the larger C-terminal region. Water molecules are shown as red spheres. Mg+2 coordination site. 3D structures of arginine kinase Arginine kinase 3D structures

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