Ascorbate peroxidase

spinqualitylabelsall models Soybean heme-containing ascorbate peroxidase complex with ascorbate and Na+ ion (purple), 1oaf Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Ascorbate peroxidase (APX) catalyzes the conversion of ascorbate and hydrogen peroxide to dehydroascorbate and water thus detoxifying hydrogen peroxide. APX is involved in the glutathione-ascorbate cycle. APX is accumulated in plants in response to heat and drought stress. APX contains a heme group. Relevance APX is part of plants antioxidant defense. APX converts H2O2 to water using ascorbate as an electron donor. APX is used in electron microscopy as a genetic tag which can be stained independently of light activation. Structural highlights The heme-containing active site of APX contains a His residue (H163 in soybean) which coordinates with the heme and confers stability to the Fe state in the heme. 3D structures of ascorbate peroxidase Ascorbate peroxidase 3D structures

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