Beta-hydroxyacyl-acyl carrier protein dehydratase

spinqualitylabelsall models Structure of FabZ (PDB code 1zhg). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase or 3-oxoacyl-ACP reductase (FabZ) catalyzes the dehydration of short and long chained β-hydroxyacyl-ACPs. FabA exhibits broad overlapping activity to FabZ and is most active in dehydrating midlength chained β-hydroxyacyl-ACPs. FabG or 3-ketoacyl-(acyl-carrier-protein) reductase or beta-ketoacyl carrier protein reductase is part of the fatty acid biosythesis elongation cycle. FabG reduces the β-keto acyl group of the elongating fatty acid. See also: Fatty acid synthesis Structural highlights The structure of FabA and FabZ shows a tunnel between the interfaces of the dimer. This tunnel accommodates the substrate. 3D structures of β-hydroxyacyl-acyl carrier protein dehydratase Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures

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