CD2-associated protein

spinqualitylabelsall models Structure of human CD2AP SH3 domain 1 (green) complex with E3 ubiquitin ligase peptide (magenta) (PDB entry 2j6o) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function CD2-associated protein (CD2AP) called also CMS, is a scaffolding protein which regulates actin cytoskeleton. CD2AP SH3 domain interacts with actin and a variety of membrane proteins. CD2AP contains in its N-terminal 3 SH3 domains followed by a proline-rich region. Disease Haploinsufficiency of CD2AP is associated with susceptibility of glomerular disease 3D structures of CD2-associated protein CD2-associated protein 3D structures

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Michal Harel, Alexander Berchansky